Estimation of dose-response curves and identification of peaks in hormone pulsations: classic marriages of statistics to science.
نویسنده
چکیده
This essay examines the historical significance of two APS classic papers that are freely available online: De Léan A, Munson PJ, and Rodbard D. Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am J Physiol Endocrinol Metab Gastrointest Physiol 235: E97–E102, 1978 (http://ajplegacy.physiology.org/cgi/reprint/235/2/E97). Merriam GR and Wachter KW. Algorithms for the study of episodic hormone secretion. Am J Physiol Endocrinol Metab 243: E310 –E318, 1982 (http:// ajplegacy.physiology.org/cgi/reprint/243/4/E310).
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ورودعنوان ژورنال:
- American journal of physiology. Endocrinology and metabolism
دوره 289 3 شماره
صفحات -
تاریخ انتشار 2005